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OBJECTIVE To verify the 17-gene Oncotype DX Genomic Prostate Score (GPS) as a predictor of damaging pathology (AP) in African American (AA) men and also to assess the circulation of GPS in AA and European American (EA) males with localized prostate cancer tumors. TECHNIQUES The study populations had been produced by two multi-institutional observational scientific studies. Between February 2009 and September 2014, AA and EA males who elected instant radical prostatectomy after a