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Here, we employed a multi-decade, continental-scale method of surveillance information to understand trends of seasonal IAV subtype diversity. Between 1976-2015, IAVs were detected in 8,427 (10.8%) of 77,969 examples from migratory waterfowl throughout the Central and Mississippi Migratory Flyways in the United States and Canada. A total of 96 hemagglutinin (HA)/neuraminidase (NA) subtype combinations had been separated, which included most HA (H1-H14) and all 9 NA sub