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This study aimed to assess the stability of compensatory treatment of Class III malocclusion in permanent dentition. Thirty-six patients (21 women and 15 men; mean age, 20years) with Class III malocclusion were subjected to the compensatory treatment of permanent dentition and followed up for at least 3years after orthodontic treatment (T3). Multivariate Poisson regression was performed to assess the influence of clinical, cephalometric, and dental cast variables at the beginning (T1) and the end of treatment on the stability of Class