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Which make liver cirrhosis and hepatocellular carcinoma (HCC) major health issues in Egypt. Circulating microRNAs (miRNAs) being examined as biomarkers for malignancies. We investigated miRNA gene expression of Lethal-7 (let-7) cluster let7-a-1, let-7d-1, let-7f-1 and miRNA (miR)143/145 cluster in sera of HCC customers and persistent HCV patients. TECHNIQUES the research included 40 post HCV-Hepatocellular carcinoma clients, 40 chronic HCV patients split into 2 subgroup

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