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ary work suggests that eliminating patient exposure to opioids in the intraoperative period does not have a deleterious effect on perioperative patient outcomes. Comorbidities influence disease assessment in axial spondyloarthritis (axSpA), but their association with response to TNF inhibitors (TNFi) is unclear. We examined associations between comorbidity history at TNFi initiation and 1) change in disease indices over time; 2) binary response definitions; 3) time-to-treatment-discontinuation. We studied participants starting their fir

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