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Atherosclerosis is one of the main reasons for adult mortality in advanced populations and countries with high stress levels. Klotho family are single-pass trans-membrane proteins that involve in the genesis and progression of various diseases, including acardiovascular disease, apoptosis and stress oxidative imbalance. Present study, investigates the pattern of changes in Klotho and FOXO1 gene expressions and levels in atherosclerosis. Present case control study consisted of 79 patients with atherosclerosis and 78 healthy controls. PBMC (peripheral

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In late December 2019, an outbreak of severe acute respiratory syndrome coronavirus 2(SARS COV-2) occurred in the city of Wuhan, the capital of the Hubei province in the central part of the People's Republic of China (Ren et al., 202. In Saudi Arabia, the first case of COVID-19 was reported in March 2, 2020. In March 8, 2020, the Saudi authorities adopted the lockdown strategy to contain the disease. The aim of this study was to determine the effectiveness of the various phases of the lockdown strategy in Saudi Arabia and its impact o