https://casey-nedergaard.feder....atedjournals.com/why
What Makes a Robot Vacuum Cleaner Best? The top robot vacuums come with a powerful motors and a bristles or rollers that are tough. They also have large dustbins as well as a long battery life. Certain models use smart mapping to identify homes, and they can pause, recharge and clean up right where they stopped. They can even set no-go zones and identify different surfaces. Object Avoidance Object detection is a key feature for robot vacuums, because it allows them avoid

https://www.selleckchem.com/pr....oducts/pf-03084014-p
Targeted protein degradation using heterobifunctional proteolysis-targeting chimera (PROTAC) compounds, which recruit E3 ligase machinery to a target protein, is increasingly becoming an attractive pharmacologic strategy. PROTAC compounds are often developed from existing inhibitors, and assessing selectivity is critical for understanding on-target and off-target degradation. We present here an in-depth kinetic degradation study of the pan-kinase PROTAC, TL12-186, applied to 16 members of the cyclin-dependent kinase (CDK)