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Sildenafil, the first of the oral phosphodiesterase type 5 inhibitors, is the only FDA-approved oral therapy for the treatment of erectile dysfunction.

Sildenafil Viagra, the first of the oral phosphodiesterase type 5 inhibitors, is the only FDA-approved oral therapy for the treatment of erectile dysfunction. The drug has been studied for other conditions including pulmonary hypertension, left ventricular dysfunction, and diabetes. In clinical trials, Viagra demonstrated an ability to enhance nitric oxide production, increase cGMP, and vasodilate blood vessels.
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