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Prompt implementation of appropriate targeted antibiotic therapy representsa valuable approach in improving clinical and ecological outcome in critically septic patients. Thismultidisciplinary opinion article aims to develop evidence-based algorithms for targeted antibiotictherapy of infection-related ventilator associated complications (IVACs) caused by ,which are among the most common pathogens associated with these conditions. A multidisciplinary team of four experts had several rounds of assessment for developingalgorithms dev