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Ovarian cancer (OC) is the leading cause of death among gynecological tumors; however, no effective treatment is currently available. Fucoidan, which is extracted from marine algae, has significant anti-cancer effects. The aim of this study was to determine the effects of fucoidan on the proliferation and apoptosis of OC cells through inhibition of the PI3K/Akt signaling pathway. Human ovarian normal epithelial cells (IOSE8 and human OC cells (SKOV-3, A2780, OVCAR-3, TOV-112D, and Caov-3) were selected to verify the safety of fucoidan at

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93, 95%CI 1.73~4.94, P0.05). There were the significant independent and interaction effects between PA and outdoor time on AL. In the future, college students' physical education can be arranged reasonably to reduce the health risks. There were the significant independent and interaction effects between PA and outdoor time on AL. In the future, college students' physical education can be arranged reasonably to reduce the health risks. Although unintentional pregnancy loss is common, national representative statistics are lacking