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How to Buy a Driving License in Germany You can only swap your license to one that is a German one if it's issued by an EU/EEA member or a country which has a special reciprocity agreement with Germany. Otherwise you need to take a theory and a practical driving test (fees vary). Make sure to book your appointment with your Burgeramt prior to when your foreign license expires. Class A If you're a new resident of Germany, you will need to obtain a class A driver's license before you are legally able to dri

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Alzheimer's disease (AD) is a heterogeneous neurodegenerative disorder with complex etiology that eventually leads to dementia. The main culprit of AD is the extracellular deposition of β-amyloid (Aβ) and intracellular neurofibrillary tangles. The protein conformational change and protein misfolding are the key events of AD pathophysiology, therefore endoplasmic reticulum (ER) stress is an apparent consequence. ER, stress-induced unfolded protein response (UPR) mediators (viz. PERK, IRE1, and ATF6) have been reported widely in the AD br