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ation of homoserine, which induces the production of an otherwise silent cytotoxin via a LuxR-type transcriptional regulator. These results provide a starting point for uncovering the molecular basis of the hormetic effects of antibiotics. Copyright © 2020 Li et al.Many patients with severe infections receive inappropriate empirical treatment, and rapid detection of bacterial antibiotic susceptibility can improve clinical outcome and reduce mortality. To this end, we have developed a multiplex fluidic chip for rapid phenotypic antibiotic

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001 in both), and higher values post-exercise (p=0.04 and p=0.002, respectively). The [LAC] was higher during exercise when high-intensity bouts were applied (p less then 0.001 for both) and higher post-exercise on the intermittent one compared to FATmax (p=0.016). The inclusion of high-intensity efforts during moderate-intensity continuous exercise promoted higher physiological demand and post-exercise fat oxidation. Novelty bullets • The inclusion of 2-min efforts modifies continuous exercise demands • Maximal efforts can increase pos