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is associated with increased mortality in patients with COVID-19. Screening for undiagnosed diabetes by HbA1c measurement should be considered in adult Chinese inpatients with COVID-19. Bardet-Biedl syndrome (BBS) is a rare autosomal recessive ciliopathy disorder. Many BBS disease-causing genetic variants have been identified due to the advancement of molecular diagnostic tools. We report on a novel pathogenic variant in a consanguineous Pakistani family with an affected child. Clinical exome sequencing was used to search for BBS causing

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The association between preeclampsia/eclampsia and HFpEF was analyzed using Cox proportional hazards models. There were 2,532,515 women included in the study 2,404,486 without and 128,029 with preeclampsia/eclampsia. HFpEF hospitalization was significantly more likely among women with preeclampsia/eclampsia, after adjusting for baseline hypertension and other covariates (aHR 2.09; 95%CI 1.80-2.44). Median time to onset of HFpEF was 32.2months (interquartile range 0.3-65.0months), and median age at HFpEF onset was 34.0 years (in