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Expecting rats were subcutaneously administered 0.2 mg/kg/d dexamethasone from gestational day (GD) 9 to GD20. Male GD20 fetuses and postnatal time 85 adult male offspring rats were sacrificed under anesthesia. Hypothalamic cells were from GD20∼postnatal time (PD) 7 fetal male rats, treated with different levels of dexamethasone and the glucocorticoid receptor (GR) antagonist mifepristone for 5 times. The results recommended that dexamethasone enhanced the exp