https://www.aceshowbiz.com/cel....ebrity/ashton_kutche
Ashton Kutcher's journey from a humble beginning on an Iowa farm to becoming a celebrated star tells a story of determination and resilience. Born in Cedar Rapids, Iowa, Kutcher was raised in a family that valued hard work and perseverance. Growing up, he helped with chores on the farm, learning the importance of diligence and effort early on in life. Even though he came from a small town, Ashton always dreamed of something more. Kutcher’s ascent to stardom wasn't immediate. Before his rise to fame, he attended the Univer

https://www.selleckchem.com/pr....oducts/17-AAG(Geldan
Neither a significant interaction with double stranded DNA nor strong inhibition of the DNA dependent enzyme topoisomerase 1 by 8 were detectable in cell free systems. Laser scanning confocal microscopy revealed that some amount of 8 was detectable in mitochondria as early as 5 min after the addition to the cells; exposure for 1 h caused significant morphological changes and clustering of mitochondria. The bioisosteric analog 2 in which the thiophene ring was replaced with furan was less active although the patterns of cyto