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The Pain Catastrophizing Scale (PCS), a widely used tool to assess catastrophizing related to spinal disorders, shows valid psychometric properties in general but the minimal important change (MIC) is still not determined. Prospective observational study. To assess responsiveness and MIC of the PCS in individuals with chronic low back pain (LBP) undergoing multidisciplinary rehabilitation. Outpatient rehabilitation hospital. Two hundred and five patients with chronic LBP. Before and after an 8-week multidisciplinary rehabilitation program