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The aim of this study was to describe macular changes associated with tilted disc syndrome (TDS) using multimodality imaging. This is a retrospective observational study of the consecutive TDS cases which were studied for macular changes using color fundus photographs and optical coherence tomography (OCT). Fundus autofluorescence, fundus fluorescein angiography, and OCT angiography were performed wherever required. Twenty consecutive TDS cases (36 eyes) were included. OCT showed inferior depression of all layers in specific scans and m