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Copyright © 2020 Hoogeveen and Boonstra.The importance of the kynurenine pathway in normal immune system function has led to an appreciation of its possible contribution to autoimmune disorders such as rheumatoid arthritis. Indoleamine-2,3-dioxygenase (IDO) activity exerts a protective function, limiting the severity of experimental arthritis, whereas deletion or inhibition exacerbates the symptoms. Other chronic disorder with an inflammatory component, such as atherosclerosis, are also suppressed by IDO activity. It is suggested

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Symptoms of ADHD in Adults Many adults with ADHD live their lives undiagnosed. Families and friends mistakenly believe that their symptoms are due to unruly behavior, bad habits or character flaws. People suffering from ADHD are often seen as restless, anxious and hurried. These symptoms can be evident in school, work and social situations. For a diagnosis of ADHD, several inattentive and hyperactive-impulsive symptoms must have been present before age 12. The symptoms must also be present in more than one s