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On the basis of the knowledge accumulated because of the Bap protein of S. aureus, this analysis is designed to review current knowledge of the dwelling and properties of each and every domain of Bap and their contribution to Bap functionality.The thermophilic crenarchaeon Sulfolobus acidocaldarius has four DNA polymerases (DNAPs) PolB1, PolB2, PolB3, and Dbh (PolY). Earlier in vitro researches recommended that PolB1 may be the main replicative DNAP of Sulfolobales whereas PolB2 and Y-family polymerases Dpo4 (Saccharolobus
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