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In 24% of the investigations, movement was recorded (acceleration 0.10 [m/s ]; angular velocity 0.018 [°/s]). In all examined regions of interest, head motion during CBCT acquisition resulted in significant impairment of image quality ( 0.001). Movement in the horizontal and vertical axes was most relevant for image quality (R 0.7). Relevant head motions during CBCT imaging were frequently detected, leading to image quality loss and potentially impairing diagnosis and therapy planning. The presented data illustrate the