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e ribosome, unclear mitochondria, and disordered distribution of collagen fibers in the extracellular matrix in the model group, which was relatively milder in both the WNM and medication groups. Compared with the medication group, the Mankin score in the WNM group was evidently lower (P0.05). WNM can effectively slow down the degeneration of cartilage and subchondral bone of KOA rabbits, delay the development of KOA. WNM can effectively slow down the degeneration of cartilage and subchondral bone of KOA rabbits, delay the develop